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Dangerous Fat Is Inherited From Fathers: Study

Medical Daily logo Medical Daily 09-09-2018 Medical Daily Staff

Father's Genes © Father's Genes Father's Genes While brown fat cells can protect against obesity by burning excess calories, too many white fat cells can have the opposite effect, leading to excess weight gain and associated health risks. New findings reveal which parent's genes lead to the development of which type of fat.

The study titled "LincRNA H19 protects from dietary obesity by constraining expression of monoallelic genes in brown fat" was published in the journal Nature Communications on Sept.7.

By examining the gene H19, the research team found it could have a unique protective effect against excess weight gain. This gene is among the monoallelic genes i.e. the one percent of genes which are inherited exclusively from either our mother or father.

Video: Surprisingly, Sugar Cravings May Indicate a Gene That Keeps Body Fat Low (Cooking Light)

According to the researchers, the gene could play an important role in the onset of diseases linked to obesity such as cardiovascular disease, atherosclerosis, liver manifestations of metabolic disease, and type 2 diabetes.

The genes people inherit from their father are linked to white tissue fat which is the type created by our body to store energy when we consume too many calories. This dangerous kind of fat is found on body parts like the stomach and thighs, which can potentially lead to metabolic diseases. 

On the other hand, genes inherited from the mother seem to lead to the development of brown tissue fat. Being the "good" kind of fat, it performs the function of converting the food we consume into body heat.

© Getty The findings aid the potential to develop interventions and strategies against diet-induced obesity. In experiments from past studies, for instance, increasing brown fat mass in mice was found to increase the rate at which they burn energy and reduce fat in their bodies. The research team behind the new study said they were "delighted" with the results.

"By using mouse models, we have identified that the gene H19 performs a form of gene control in brown fat cells. We have been able to demonstrate that an overexpression of the H19 gene in mice protects against obesity and insulin resistance," said Professor Jan-Wilhelm Kornfeld from the Department of Biochemistry and Molecular Biology at the University of Southern Denmark.

© Getty "In addition, we have been able to detect similar patterns of gene control in obese people. We, therefore, believe that our results can be the first step towards developing groundbreaking new and improved treatments for obesity-related diseases," the professor added.

Earlier this year, Harvard researchers also found that a mother's adherence to an overall healthy lifestyle can help in lowering the risk of obesity in their children. The recommended healthful habits included regular physical activity, eating a nutritious diet, drinking alcohol in moderation, avoiding smoking, and maintaining a healthy body weight.

Gallery: There's a big difference between good and bad fat — here's how to pick the best heart-healthy fats (Business Insider)

Disclaimer: Views expressed in this article are the author's own and MSN does not endorse them in any way. Neither can MSN independently verify any claims made in the article. You should consult your physician before starting any weight loss or health management programme to determine if it is right for your needs.

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