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Scientists Reverse Brain Damage in Drowned U.S. Toddler

Newsweek logo Newsweek 7/19/2017 Hannah Osborne

© Provided by IBT Media Eden was submerged in 5 degree Celsius for 15 minutes and was unresponsive after being resuscitated.

In what is believed to be a world first, scientists have reversed brain damage in a toddler that drowned in a swimming pool. Using oxygen therapy, scientists were able to restore her ability to walk and talk just months after the accident, in which she spent 15 minutes submerged in a swimming pool and two hours where her heart did not beat on its own.

The accident took place in February 2016. Two-year-old Eden Carlson had managed to get through a baby gate and fall into the family swimming pool and was in the 5 degree Celsius water for up to 15 minutes before being discovered.

After being resuscitated and treated in hospital for just over a month, she was unresponsive to all stimuli. She was immobile and constantly squirmed and shook her head. MRI scans showed deep injury to the brain’s gray matter, as well as loss of white and gray matter.

In a bid to reverse the brain damage, researchers at the LSU Health New Orleans School of Medicine and the University of North Dakota School of Medicine began treating her with two types of oxygen therapy.

This includes normobaric oxygen therapy, where levels of oxygen given are the same as at sea level, and hyperbaric oxygen therapy (HBOT), where they are given pure oxygen at pressures higher than that of the atmosphere within a special chamber.

(Video by AccuWeather)


Fifty five days after the drowning accident, doctors started giving Eden normobaric oxygen for 45 minutes twice per day. This appeared to make her more alert and awake, and she stopped squirming. She started laughing more and was able to move her arms and hands, and grasp with her left. Scientists also noted eye-tracking movements and some speech.

After 78 days, Eden began HBOT therapy, with 45 minute sessions five days per week for four weeks. After 10 sessions, her mother said she was almost back to normal other than motor function. After 39 sessions—coupled with physical therapy—Eden was able to walk and her speech had returned to normal. Her cognitive abilities had improved and motor function was almost restored to pre-drowning levels.

An MRI scan a month after the 40th HBOT session showed almost complete reversal of the brain damage initially recorded. Researchers believe the oxygen therapy, coupled with Eden having the developing brain of a child, had activated genes that promote cell survival and reduce inflammation—allowing the brain to recover. The case report is published in the journal Medical Gas Research.

Paul Harch, who treated Eden, said in a statement: “The startling regrowth of tissue in this case occurred because we were able to intervene early in a growing child, before long-term tissue degeneration. Although it’s impossible to conclude from this single case if the sequential application of normobaric oxygen then HBOT would be more effective than HBOT alone, in the absence of HBOT therapy, short duration, repetitive normobaric oxygen therapy may be an option until HBOT is available."

Concluding, the researchers say that to their knowledge, this is the first reported case of gray matter loss and white matter atrophy (types of brain damage) reversal with any therapy and that treatment with oxygen should be considered in similar cases. “Such low-risk medical treatment may have a profound effect on recovery of function in similar patients who are neurologically devastated by drowning."

Gallery: The Ultimate Guide to Pool Safety With Kids (by PopSugar) The Ultimate Guide to Pool Safety With Kids: <p>Hitting the pool with kids can create some of the best Summer memories between you and your little ones. As your children gets older, many parents start to feel more relaxed around the water, especially after their kiddos officially learn to swim, but spending time by the water can still present dangers that parents need to be familiar with. From <a href="">drain entrapment</a> to <a href="">dry drowning</a> and <a href="">secondary drowning</a>, there are a variety of issues that parents need to be aware of before their kids cannonball into the water in order to ensure that they have a safe experience every time.</p><p>Whether you own a residential pool or frequent a public facility, this is the ultimate guide for navigating the pool as a parent. </p><p>Related<br><a href="">Mom's Plea About the Overlooked Pool Danger That Almost Killed Her Girl</a></p> The Ultimate Guide to Pool Safety With Kids


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