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Giants vs. Reds odds, prediction, line: 2022 MLB picks, Sunday, May 29 best bets from proven model

CBS Sports logo CBS Sports 5/29/2022 CBS Sports Staff
Oct 4, 2019; Los Angeles, CA, USA; Washington Nationals pitcher Max Scherzer (31) throws in relief in the 8th inning against the Los Angeles Dodgers in game two of the 2019 NLDS playoff baseball series at Dodger Stadium. Photo by Robert Hanashiro, USA TODAY Staff © Provided by CBS Sports

Oct 4, 2019; Los Angeles, CA, USA; Washington Nationals pitcher Max Scherzer (31) throws in relief in the 8th inning against the Los Angeles Dodgers in game two of the 2019 NLDS playoff baseball series at Dodger Stadium. Photo by Robert Hanashiro, USA TODAY Staff

The San Francisco Giants and Cincinnati Reds get to work early on Sunday in the final game of a three-game series at Great American Ball Park. The Reds (16-30) have been on a solid run after starting the season as the worst team in the majors. They won the series opener 5-1 on Friday night and pegged the tying run at the plate for the final out of a 3-2 win Saturday. The Giants (24-21) were hoping for a bit of a reprieve after a span that included series with the Cardinals, Padres and Mets, but Cincinnati has been formidable. Both teams are expected to go with right-handed starters who have been giving up a lot of runs, with Alex Cobb slated for the Giants and Tyler Mahle on the mound for the Reds.

First pitch in Cincinnati is scheduled for 11:35 a.m. ET. San Francisco is listed as a -145 favorite (risk $145 to win $100) on the money line in the latest Giants vs. Reds odds from Caesars Sportsbook, while the over-under for total runs scored is nine. Before making any Reds vs. Giants picks, you need to see the MLB predictions and betting advice from SportsLine's advanced computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times and it is off to a strong start to the 2022 season. It's on a 41-30 roll on top-rated MLB money-line picks through seven weeks, returning almost $600 for $100 players. Anyone following it has seen huge returns.

Now, the model has set its sights on Giants vs. Reds and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Here are several MLB odds and betting lines for Reds vs. Giants:

  • Reds vs. Giants money line: Cincinnati +125, San Francisco -145
  • Reds vs. Giants over-under: 9
  • Reds vs. Giants run line: Giants -1.5 (+115)
  • Reds vs. Giants tickets: See tickets at StubHub
  • CIN: The Reds are 6-8 ATS as a home underdog
  • SF: The Giants are 10-4 ATS as a road favorite
Featured Game| Cincinnati Reds vs. San Francisco Giants
Moneyline
Spread
Total
CIN
+130
BET NOW
+1.5
-120
BET NOW
o9
+105
BET NOW
SF
-150
BET NOW
-1.5
+100
BET NOW
u9
-125
BET NOW

Why you should back the Giants

Mahle comes in with an ERA of 6.32 and a 1.49 WHIP and has walked 23 in 47 innings. The Reds have the worst overall ERA in the majors, and the Giants can take advantage. San Francisco is third in MLB in runs scored (226) and put a lot of runners on base, averaging 3.9 walks per game (second) and posting a .733 OPS (third). Joc Pederson (11 homers) and Wilmer Flores (10 doubles) have been hitting for power and have driven in a combined 51 runs. 

Thairo Estrada, who leads the team with 41 hits, and outfielder Darin Ruf, who is fourth in MLB with 28 walks, also should play big roles on Sunday. Mike Yastrzemski is still seeking his power after hitting 25 homers last year, but he is batting .308. Cobb has been performing well aside from his bloated ERA, striking out 39 and walking nine in 31 2/3 innings. The veteran has an expected ERA of 1.93 but is at 6.32, largely because of a .411 BABIP, which is the highest in the majors among pitchers with at least 100 batters faced. 

Why you should back the Reds

Cincinnati has been on a solid run and dropped 20 runs on the Cubs on Thursday. Cobb has clearly been scuffling, so the Reds will try to take advantage. The Giants have allowed the third-most hits in the majors (412) and have the seventh-highest WHIP in MLB (1.36). The Reds don't hit for power, with their 41 home runs below the league average, but they have 76 doubles, eighth-most in MLB. The Giants allow 14 total bases per game, fifth-most in the majors, and their bullpen has also struggled this year, posting a 4.53 ERA (fifth-worst).

Tyler Stephenson has been the Reds' best hitter, hitting .308 with an .864 OPS and driving in 24 runs. Kyle Farmer, Brandon Drury and Tyler Naquin all have at least 10 doubles, and Drury has eight homers and a team-high 26 RBI. Joey Votto got off to a horrific start and is batting .162, but both of his home runs and six of his nine RBI have come in the past seven games. Mahle has a 6.32 ERA but was at 3.75 last season, and he has 50 strikeouts in 10 starts, so if he can avoid walks (23 so far), he can be effective. He has given up three runs or fewer in six starts.

How to make Reds vs. Giants picks

SportsLine's model is leaning over on the total, projecting 10 combined runs. It also says one side of the money line has all the value. You can only get the MLB model's picks at SportsLine.

So who wins Giants vs. Reds? And which side has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks, and find out.  

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