You are using an older browser version. Please use a supported version for the best MSN experience.

After Buffalo beat Minnesota as 17-point underdogs, here are the 11 other biggest upsets in NFL history

Touchdown Wire Logo By Chris Chase of Touchdown Wire | Slide 1 of 13: On Sunday, the winless Buffalo Bills pulled off one of the biggest upsets in NFL history, defeating Kirk Cousins and the Minnesota Vikings 27-6 after entering the game as 17-point underdogs. The last time such a big underdog won a regular-season game was in 1995 and there are only very few instances of it happening throughout recorded history. According to Pro Football Reference, it's only the seventh time since the merger that a favorite of 16 points or greater lost a game in 117 chances. (Since point spreads can vary and because records of odds from before 1980 can be spotty, you may have seen different statistics than the ones mentioned above and below. PFR is the most reliable NFL database on the internet so we'll treat its numbers accordingly.) Without further adieu, here are the 12 biggest upsets in NFL history, ranked.

On Sunday, the winless Buffalo Bills pulled off one of the biggest upsets in NFL history, defeating Kirk Cousins and the Minnesota Vikings 27-6 after entering the game as 17-point underdogs. The last time such a big underdog won a regular-season game was in 1995 and there are only very few instances of it happening throughout recorded history. According to Pro Football Reference, it's only the seventh time since the merger that a favorite of 16 points or greater lost a game in 117 chances. (Since point spreads can vary and because records of odds from before 1980 can be spotty, you may have seen different statistics than the ones mentioned above and below. PFR is the most reliable NFL database on the internet so we'll treat its numbers accordingly.) Without further adieu, here are the 12 biggest upsets in NFL history, ranked.
© File photo

MORE FROM TOUCHDOWN WIRE

Touchdown Wire
Touchdown Wire
image beaconimage beaconimage beacon