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Hypertension Treatment: Challenges On Blood Pressure

Longevity logo Longevity 2018-05-31 Editor LL

hypertension | Longevity LIVE: davide-ragusa-225093-unsplash © Provided by ZA Celebrityworx Pty Ltd davide-ragusa-225093-unsplash While the World Hypertension League’s 2017 theme of ‘Know your numbers’ calls attention to awareness and prevention, those treating and managing hypertension may give a thought at this time to the long-term impact of the disease and its treatment.  According to the World Health Organization, hypertension accounts for more than 5.8% of total deaths, 1.9% of years of life lost and 1.4% disability-adjusted life years all over the world. These figures are more dramatic in the formerly socialist economies’ countries. Mortality reduction should be the ultimate goal of antihypertensive treatment. 

ACE inhibitors (AECIs) are one of the first line treatment options for uncomplicated primary hypertension. Despite their positive impact on mortality reduction, ACEIs have been shown to reduce the levels of vitamin D3 in the body. 

Long-term use of ACEIs also results in the depletion of zinc, which may complicate the clinical features of atherosclerosis, amongst other effects. Diseases such as diabetes, heart failure and hypertension might also enhance zinc deficiency.

Vitamin D and zinc play a role in the Renin Angiotensin System (RAS) system which regulates blood pressure. Inappropriate stimulation of RAS has been associated with the pathogenesis of hypertension, heart attack, stroke and hypertrophy of the left ventricle and vascular smooth muscle cells. This may increase the risk of death from stroke, coronary heart disease and heart failure. Awareness of the potential depletion of these nutrients, as a result of hypertension, or the treatment thereof, leads to the question of how to best handle this problem. Exposure to sunlight and food sources such as oily fish, offer an option for the replacement of vitamin D3., while oysters, red meat and poultry offer supplementation sources for zinc. 

A relatively new range of supplements marketed by the OTC division of Adcock Ingram includes a presentation especially formulated for use in patients who are on antihypertensive treatment. ACEI-GAP assists in the maintenance of the essential nutrients that may be depleted as a result of hypertension and the treatment thereof. Containing vitamin D3 and zinc, ACEI-GAP is an adjunct to antihypertensive therapy with ACEIs, and hence the name ACEI-GAP.

The vitamin D3 and zinc contained in ACEI-GAP, are the essential nutrients that may be depleted as a result of hypertension and the treatment thereof with ACEIs. ACEI-GAP is formulated to offer a convenient once daily dosage and each capsule contain 800 international units of vitamin D3 and 15 milligrams of zinc. 

All the products in the GAP range are supported by clinical data and have been formulated to offer a convenient single daily dosage. Click here to find out more.

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Related: Don't ignore these symptoms - see a doctor right away (Provided by Wochit News)

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