You are using an older browser version. Please use a supported version for the best MSN experience.

Black Fungus Treatment: Centre issues guidelines for mucormycosis management in children

Jagran English logo Jagran English 5 days ago Jagran English

Representational image © Ritesh Shukla/Getty Images Representational image Amid the increasing cases of COVID-19-triggered Black Fungus (Mucormycosis) across the country, the Ministry of Health on Thursday issued the guidelines for the management of the fungal infection in children below 18 years of age. 

FULL COVERAGE: Coronavirus crisis in India

Mucormycosis is a serious fungal disease seen in patients with underlying/predisposing factors such as immunosuppression, poorly controlled diabetes mellitus, misuse/overuse of steroids, cancer, organ/stem cell transplantation, and those under prolonged ICU treatment, as per the Ministry of Health.

"Do not wait for culture results to initiate therapy as mucormycosis is an emergency. Early complete surgical debridement is the cornerstone of treatment, and may be repeated as required," the DGHC said in its guideline.

As per the guidelines issued by the government, "Conventional Amphotericin B as a prolonged IV infusion through a central venous catheter or PICC; closely monitor kidney function and electrolytes during treatment".

"Reconstitute in water for injection, and dilute in 5 per cent dextrose (do not use normal saline/Ringer's lactate, start with test dose: 1 mg IV infusion over 20-30 minute. Loading dose: 0.25-0.5 mg/kg IV infused over 2-6 hours; gradually increase by 0.25 mg-increments/day to reach maintenance dose: 1-1.5 mg/kg/day," the guidelines further stated. 

Also watch: WTO members agree to talks on patent waiver for Covid drugs, vaccines (Video by The Times of India)

Replay Video

"Liposomal Amphotericin B or Amphotericin lipid complex, if available; prolonged infusion over 2-3hours through a central venous catheter or PICC and closely monitoring KFT and electrolytes. Reconstitute in water for injection, and dilute in 5 per cent dextrose (do not use normal saline/Ringer's lactate); start full dose from first day; 5 mg/kg/day (10 mg/kg/day in case of CNS involvement)," it added.

"Posaconazole should be given as salvage therapy in cases who cannot be given Amphotericin B. Children less than 11 years in age dose - 7-12 mg/kg/dose IV twice on the first day and maintenance dose - 7-12 mg/kg IV once a day, starting on the second day," the guidelines said.

Mucormycosis can be life-threatening in diabetic or severely immuno-compromised individuals such as cancer patients or people with HIV/AIDS. The doctors in India are documenting an alarming number of cases of Mucormycosis among patients with COVID-19 and those who have recently recovered. They believe that Mucormycosis may be triggered by the use of steroids, a life-saving treatment for severe and critically ill COVID-19 patients. 

Follow the government's latest guidance on safeguarding yourself during the coronavirus pandemic, including travel advice within and outside the country. The World Health Organization has also busted some myths surrounding coronavirus. The Ministry of Health's special helpline is available at +91-11-23978046, ncov2019@gmail.com and ncov2019@gov.in.

More from Jagran English

Jagran English
Jagran English
image beaconimage beaconimage beacon