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New research finds that berries may contain cancer-fighting compounds

Relaxnews (AFP) logoRelaxnews (AFP) 6/4/2018

New European research has discovered that berries may offer another benefit for health, increasing the function of an enzyme which could reduce the growth of cancer cells. © Provided by AFPRelaxNews New European research has discovered that berries may offer another benefit for health, increasing the function of an enzyme which could reduce the growth of cancer cells. New European research has found that a naturally occurring pigment in berries could increase the function of an enzyme which reduces the expression of cancer genes and cancer cell growth.

Carried out by the University of Eastern Finland, the study looked at the effect of the pigments that give berries their color, known as flavonoids, on the function of the sirtuin 6 (SIRT6) enzyme in cancer cells.

Sirtuins are enzymes which regulate the expression of genes that control the function of cells. The aging process can change sirtuin function, which can contribute to the development of various diseases.

As flavonoids are known to have an antioxidant effect on the body and provide important health benefits, the team wanted to see if they could affect the function of SIRT6, which has been linked to longevity, metabolism, DNA-repair, and reduced inflammation.

The researchers found that cyanidin, a compound which belongs to a group of flavonoids known as anthocyanidins, increased SIRT6 enzyme levels in human colorectal cancer cells, decreased the expression of two cancer genes, and increased the expression of a tumor suppressing gene in cells.

The findings suggest that cyanidin, which is found in wild bilberry, blackcurrant and lingonberry, could potentially be used in future cancer treatments, such as drugs that regulate SIRT6 function.

The study is not the first to suggest that berries could have a positive effect on health, the fruits have long been touted for their health benefits and their potential to prevent a variety of other diseases and conditions.

A large-scale 2016 study published in The British Medical Journal which followed 124,086 men and women across the US found that those who had a high intake of flavonoids, such as anthocyanins found in blackberries, blackcurrants, blueberries and strawberries, gained less weight over a 24-year period. 

Another study published the same year which followed 50,000 middle-age men also found that a diet rich in flavonoids could reduce the risk of erectile dysfunction by 14%. Of the six flavonoids studied, three in particular appeared to be the most beneficial, including anthocyanins.

Research from Poland also found that blackberries, raspberries, and the lesser-known black raspberry, all had a high level of antioxidant activity that could be beneficial in boosting health. Antioxidants are thought to decrease or reverse the effects of free radicals, the natural byproducts of energy production that are closely linked with heart disease, cancer, arthritis, stroke and respiratory diseases, with black raspberries found in the study to have a level three times higher than red raspberries or blackberries. 

Other small-scale studies have also linked berries to improved cognitive function, improved attention, better mood, better memory, and decreased mental fatigue, with some researchers suggesting that the beneficial effects could also help decrease the risk of Parkinson's disease, Alzheimer's disease, stress, anxiety and even depression.

The findings of the new research can be found published online in the journal Scientific Reports.

Gallery: 40 best superfoods for people over 40 (courtesy Eat This! Not That!) 40 Best Superfoods for People Over 40: The picks that’ll help keep your blood sugar in check, slash your cancer risk, and keep energy levels high after you’ve hit the big 4-0. As we age, it becomes increasingly more difficult to combat chronic diseases, maintain a healthy, and keep belly fat at bay. But contrary to what you may believe, your health isn’t actually doomed to plummet downhill with every turned page of the calendar. Sure, you may not be able to cut out bread for a week and lose pounds like you did in your twenties, but you certainly can add specific foods—like the ones below—to your diet in your quest to turn back time.Choosing these youth-promoting foods will equip your body with the cancer-fighting, wrinkle-smoothing, and metabolism-revving vitamins and nutrients it needs to help you look and feel young and vibrant—all without the help of a plastic surgeon. So next time you head out for a grub run, make sure to stock up on our stellar list of superfoods to eat after 40, while practicing restraint when it comes to ordering these 40 Meals You Should Never Eat After 40. 40 Best Superfoods for People Over 40

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