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Saints vs. Chargers odds, line: Monday Night Football picks, predictions from model on 103-69 roll

CBS Sports logo CBS Sports 10/12/2020 CBS Sports Staff
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The Los Angeles Chargers are out to break a five-game losing streak on Monday Night Football when they take on the New Orleans Saints in the second-to-last game of Week 5. The Chargers have also dropped two straight road games on Monday Night Football. Los Angeles' last win on a Monday was in 2013 in San Diego against the Indianapolis Colts. The Chargers have a minus-three point differential this season, while the Saints are at zero.

Kickoff from the Superdome is set for 8:15 p.m. ET. Los Angeles will be without running back Austin Ekeler (hamstring), while New Orleans will be without star wideout Michael Thomas. New Orleans is a seven-point favorite in the latest Saints vs. Chargers odds from William Hill after the line opened at 7.5, while the over-under is 49.5. Before making any Chargers vs. Saints picks, check out the latest NFL predictions from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up over $7,300 for $100 players on top-rated NFL picks since its inception five-plus years ago. It's off to a strong 7-4 roll on top-rated NFL picks this season. The model enters Week 5 on an incredible 103-69 run on top-rated NFL picks that dates back to the 2017 season.

The model ranked in the Top 10 on NFLPickWatch in three of the past four years on straight-up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up. 

Now, the model has set its sights on Chargers vs. Saints. You can visit SportsLine now to see the picks. Here are the NFL odds from William Hill and trends for Saints vs. Chargers:

  • Chargers vs. Saints spread: Saints -7
  • Chargers vs. Saints over-under: 49.5 points
  • Chargers vs. Saints money line: Chargers +260, Saints -320
  • LAC: Has allowed a red zone touchdown percentage of 42.9, third-best in the NFL
  • NO: Over has hit in all four Saints games this season

Why the Saints can cover


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New Orleans' defense is ranked sixth in the NFL, allowing 334.3 yards per game. A big reason for that is the play of defensive end Cameron Jordan. He had a sack last week and had a sack and a forced fumble in the last meeting against the Chargers.

Jordan will look for his third game in a row with a sack against Los Angeles. He also has a sack in two of his last three games on Monday Night Football. 

Linebacker Demario Davis is also a difference-maker with 26 tackles, including 20 solo. He has two sacks for 20 yards and four tackles for loss to go along with one pass breakup. Davis has at least six tackles in two of his last three games against the Chargers and has five pass breakups in his past four games on MNF.

Why the Chargers can cover

Defensively, Los Angeles cornerback Casey Hayward Jr. is expected to appear in career game No. 200. Hayward is third on the team in tackles with 21, including 18 solo, with three pass breakups. He had five tackles last week against the Buccaneers. He is looking for his third road game in a row with five or more tackles. For his career, he has 22 interceptions and 96 pass breakups. 

Also leading the way on defense is linebacker Kyzir White, who has been a beast with 30 stops, including 22 solo. He also has 2.5 tackles for loss and one pass breakup. Last week, he had 10 tackles and a pass breakup. For his career, White has 87 tackles, including 59 solo, with two picks.

How to make Saints vs. Chargers picks

SportsLine's model is leaning over the total. In fact, it says Herbert will throw for nearly 300 yards and two touchdowns, while Brees will throw for nearly 250 yards and at least two scores. It has also generated an against-the-spread pick that cashes in well over 50 percent of simulations. You can only get the pick here

So who wins Chargers vs. Saints on Monday Night Football? And which side of the spread cashes in well over 50 percent of simulations? Visit SportsLine now to see which side of the Chargers vs. Saints spread to jump on, all from the advanced model that is up over $7,300 on its NFL picks over the past five seasons, and find out.

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